Kune marudzi akawanda ezvokudya, refu rekupa cheni, uye kuomerwa mukutarisira kuchengeteka. Detection tekinoroji inzira yakakosha yekuchengetedza chikafu. Nekudaro, matekinoroji ekuona aripo anotarisana nematambudziko mukuonekwa kwekuchengetedza chikafu, senge kusanyanya kurongeka kwezvinhu zvakakosha, sampuli refu isati yarapwa nguva, yakaderera kupfumisa kushanda zvakanaka, uye yakaderera kusarudzwa kwezvinhu zvakakosha zvekuona senge mass spectrometry ion masosi, izvo zvinoguma nechaiyo-nguva kuongororwa kwemasampuri echikafu. Takatarisana nematambudziko, timu yedu huru yenyanzvi inotungamirwa naZhang Feng yakawana akateedzana ebudiriro tekinoroji munzira yekutsvagisa yezvinhu zvakakosha, zvinhu zvakakosha, uye nzira itsva dzekuedza kuchengetedza chikafu.
Panyaya yekutsvagisa zvinhu zvakakosha uye kusimudzira, timu yakaongorora iyo chaiyo adsorption mashandiro e pre-ekurapa zvinhu pazvinhu zvinokuvadza muchikafu, uye yakagadzira nhevedzano yeakanyanya adsorption micro nano chimiro pre-kurapa zvinhu. Kuonekwa kwezvinhu zvinonangwa padanho rekutsvaga/ultra trace zvinoda kufanorapwa kuti zvipfume nekucheneswa, asi zvinhu zviripo zvine hushoma hwekupfumisa hunyanzvi uye husina kukwana hunhu, zvichikonzera kunzwisiswa kwekuona kusazadzisa zvinodiwa zvekuonekwa. Kutanga kubva pachimiro chemolecular, timu yakaongorora iyo chaiyo adsorption mashandiro e pre-ekurapa zvinhu pazvinhu zvinokuvadza muchikafu, yakaunza anoshanda mapoka senge urea, uye akagadzira akatevedzana ezve covalent organic framework zvinhu zvine makemikari bond regulation. Inoshandiswa kupfumisa uye kucheneswa kwezvinhu zvinokuvadza zvakaita seaflatoxins, fluoroquinolone veterinary drugs, uye phenylurea herbicides muchikafu, nguva isati yarapwa inopfupikiswa kubva pamaawa mashoma kusvika kumaminitsi mashoma. Kuenzaniswa nemaitiro enyika, kunzwisiswa kwekuona kunowedzera kanopfuura kane zana, kuputsa kuburikidza nezvinetso zvehutano zvehurombo hwezvinhu zvinotungamirira kumatambudziko ekutanga kurapwa uye kuderera kwekunzwa kwekunzwa, izvo zvakaoma kuzadzisa zvinodiwa zvekuona.
Mukutsvagisa nekusimudzira kutungamira kwezvikamu zvakakosha, timu ichapatsanura zvinhu zvitsva uye nekuzvibatanidza ne mass spectrometry ion masosi kugadzira yakanyanya kusarudzwa mass spectrometry ion source components uye real-time mass spectrometry nzira dzekuona dzekukurumidza. Parizvino, iwo anowanzo shandiswa colloidal goridhe bvunzo mitsetse ye-on-saiti yekukurumidza kuongororwa idiki uye inotakurika, asi iwo emhando uye kuwanda kwechokwadi kwakadzikira. Mass spectrometry ine mukana wekurongeka kwepamusoro, asi zvishandiso zvakakura uye zvinoda kureba sampuli pretreatment uye chromatographic kupatsanurwa maitiro, zvichiita kuti zviome kushandisa pa-saiti kuona nekukurumidza. Chikwata ichi chapaza bhodhoro reiyo iripo chaiyo-nguva misa spectrometry ion masosi iine ionization basa, uye yakaunza nhevedzano yekuparadzanisa zvinhu zvekugadzirisa matekinoroji mumisa spectrometry ion masosi, zvichiita kuti ion masosi ave nebasa rekuparadzanisa. Inogona kuchenesa yakaoma matrices akadai sechikafu ichi ionizing yakanangana nezvinhu, ichibvisa iyo inorema chromatographic kupatsanurwa pamberi pechikafu misa spectrometry kuongororwa, uye kugadzira nhevedzano yekuparadzanisa ionization yakabatanidzwa real-time mass spectrometry ion masosi. Kana iyo yakagadzirwa molecularly imprinted material yakasanganiswa ne conductive substrate kugadzira new mass spectrometry ion sosi (sezvinoratidzwa mumufananidzo 2), chaiyo-nguva mass spectrometry yekukurumidza yekuona nzira inotangwa yekuona carbamate esters muchikafu, ine kukurumidza kwekuona kwe ≤ 40 seconds uye chiyero chehuwandu hwekusvika μ chiyero chenyika yeG / 5. yakaderedzwa kubva kumakumi emaminitsi kusvika kumakumi emasekonzi, uye kunzwisiswa kwakagadziridzwa nekanenge ka20, kugadzirisa dambudziko rehunyanzvi rekusakwana kwakaringana mune-saiti chikafu chekuchengetedza tekinoroji.
Muna 2023, timu yakawana zvakatevedzana muhunyanzvi hwekuyedza kuchengetedza chikafu, kugadzira 8 nyowani yekunatsa uye yekupfumisa zvinhu uye 3 nyowani mass spectrometry ion sosi zvinhu; Nyorera pamatendi gumi nemashanu ekugadzira; 14 mvumo yekugadzira patents; Yakawana 2 software copyrights; Yakagadzira 9 zviyero zvekuchengetedza chikafu uye yakaburitsa zvinyorwa makumi maviri neimwe mumagazini epamba nekunze, kusanganisira 8 SCI Zone 1 TOP zvinyorwa.